The Genome of Setaria digitata: A Cattle Nematode Closely Related to Human Filarial Parasites
نویسندگان
چکیده
منابع مشابه
In silico characterization of a RNA binding protein of cattle filarial parasite Setaria digitata
Human lymphatic filariasis (HLF) is a neglected tropical disease which threatens nearly 1.4 billion people in 73 countries worldwide. Wuchereria bancrofti is the major causative agent of HLF and it closely resembles cattle filarial parasite Setaria digitata. Due to difficulties in procuring W. bancrofti parasite material, S. digitata cDNA library has been constructed to identify novel drug targ...
متن کاملOxidative activities in mitochondria-like particles from Setaria digitata, a filarial parasite.
The oxidative metabolic potential of Setaria digitata, a filarial parasite found in the intraperitoneal cavity of cattle, was investigated. These worms showed active wriggling movements which were not affected by respiratory poisons such as cyanide, rotenone and malonate. They also possessed cyanide-insensitive and glucose-independent oxygen consumption pathways. By differential centrifugation ...
متن کاملSuccinate oxidase and fumarate reductase systems of filarial parasite Setaria digitata.
Activities of succinate oxidase, fumarate reductase (FR) and succinate dehydrogenase (SDH) under a set of defined conditions were determined in the mitochondrial isolate from Setaria digitata, the filarial parasite from the cattle Bos indicus. Presence of only two activities namely SDH and succinate--UQ reductase of the succinate oxidase system could be detected in S. digitata. In the absence o...
متن کاملFilarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor.
Filarial nematode parasites establish long-term chronic infections in the context of an antiparasite immunity that is strongly biased toward a Th2 response. The mechanisms that lead to this Th2 bias toward filarial antigens are not clear, but one possibility is that the parasites produce molecules that have the capacity to proactively modify their immunological environment. Here we report that ...
متن کاملSetaria digitata infections in cattle: parasite load, microfilaraemia status and relationship to immune response.
A total of 110 cattle were examined in an area endemic for Bancroftian filariasis for the prevalence of infection of the bovine filarial parasite Setaria digitata. About 12.5% of cattle were found to harbour both adult worms in the peritoneum and microfilariae (mf) in circulation; 70% of the cattle were amicrofilaraemic but with an adult worm infection. A third group of cattle (16.5%) was free ...
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2020
ISSN: 1759-6653
DOI: 10.1093/gbe/evaa017